DECIPHERING MONKEY POX: A TRANSDISCIPLINARY REVIEW OF ITS EVOLUTIONARY ORIGINS, VIRAL MECHANISMS, CLINICAL DIVERSITY, AND THE ARCHITECTURE OF GLOBAL PREPAREDNESS

Abstract

Monkeypox is a zoonotic ailment resulting from the infection with the monkeypox virus, also known as MPXV, which became an important health issue of the present days. This review aims at giving a comprehensive update on monkeypox and discuss aspects such as history, virology, pathogenicity, clinical features, diagnosis, therapeutic measures and control. The recent outbreak in the global platform in the year 2024 has brought out the aspect of this formerly neglected tropical ailment to the light, thereby demanding further research and study. This article provides a state of art review of monkeypox, ongoing research and new directions in management and prevention of monkeypox as an emerging zoonotic disease. This paper is intended to be a reference for members of the healthcare profession and public health, and researchers, as a consolidation of evidence and existing and new knowledge surrounding monkeypox to allow for better preparedness and response strategies relating to the virus on a global scale.